[PDF] Dalmatian Sage (Salvia officinalis L.): A Review of Biochemical Contents, Medical Properties and Genetic Diversity | Semantic Scholar (2024)

The aim of this work is to review the literature on ecology, cultivation, composition and utilization of Salvia officinalis L. a standard literature search was performed using several electronic databases for identification of peer-reviewed articles.

The results confirm the potential use of understudied Salvia species as promising sources of antioxidant compounds for developing novel pharmaceutical, nutraceutical, or cosmeceutical products.

A critical assessment of the available data was made and perspectives for the use of white sage preparations in modern phytomedicine were discussed, as well as reports on chemistry, bioactivity, and bioavailability of S. apiana constituents.

The examined essential oils generally exhibited limited antimicrobial effects, with the exception of HC oil, which demonstrated an exceptionally impressive level of antifungal activity.

Results presented here may suggest that the essential oil of S. brachyodon possess antimicrobial properties, and is, therefore, a potential source of antimicrobial ingredient in food and pharmaceutical industry.

The obtained results revealed that the tested samples possess remarkable antibacterial activities and could be used to develop pharmaceutical formulations as an alternative to conventional antibiotic therapy.

The obtained results confirm the potential of S. transsylvanica and S. glutinosa as promising sources of bioactive compounds and as a starting point for further analyses, and confirm the antimicrobial, antifungal and cytotoxic effects using in vitro assays.

The neurobiological effects of SO on the central nervous system will be reviewed, including analgesic, memory enhancing, neuroprotective, anticonvulsant, anti-addictive, sedative, anxiolytic, and skeletal muscle relaxant effects.

The bioactive profile of various sage preparations depending on the extraction techniques and extraction parameters are described, and the newest research findings on its health effects are listed.

DMs are reclassified based on their technical principles and will be revisited emphasizing on their use in Salvia, as well as genome-wide genetic markers and molecular markers for secondary metabolites.

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Sage (Salvia species) has been used as a herb with beneficial healing properties for millennia and was found to be an active ingredient in combined plant preparations for treatment of acute and chronic bronchitis.

This study has found that autumn or winter was the best harvest time to obtain oils with high thujone levels, and major seasonal changes were found in the composition of oil distilled from a flowering type of Dalmatian sage.

The essential oil showed a temporary bacteriostatic effect on Escherichia coli, Salmonella typhi, as well as Pseudomonas aeruoginosa, but the efficiency of S. officinalis essential oil was much better, especially against bacteria resistant to antibiotic.

In this study, sage teas prepared from commercially available products were chemically analyzed for polyphenolic content using liquid chromatography, for antioxidant potential using the oxygen radical absorbance capacity method, and for the Folin–Ciocalteu index.

Differences in essential oils of 25 indigenous populations of Dalmatian sage are proposed to be mostly genetically controlled, since potential environmental factors were controlled in this study.

The obtained results indicate that antiviral activity of 144/5 involves inhibition of the early steps of the virus infective cycle without a direct virucidal effect.

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